'Click' below Quick Select

Prescription Products

Denosyl Tablets

Dietary supplement to provide antioxidant protection of the liver and the other important body tissues in dogs and cats

Description and pack sizes

Action
S-Adenosylmethionine is a molecule that is normally found in animals and is synthesized by many cells in the body using methionine supplied in the diet and ATP that is produced in the body by the animal from the other nutrients it eats. It is an essential part of a number of important metabolic pathways and therefore is particularly important in the liver because of the central role played by this organ in the metabolism of the animal.

Dosage
Because the tablet must be kept intact to prevent destruction by stomach acid, administration range is based on the nearest whole tablet (refer table). Daily administration is based on 20 mg/kg BW of S-Adenosylmethionine and rounded to the closest tablet size or combination of sizes.

Denosyl for cats and small dogs	Body Weight (kg) Up to 5.9 kg	1 tablet
Denosyl for Medium Dogs	Body Weight (kg)
	6 to 15.9	1 tablet
	16 to 29.9	2 tablets*
	*Or 1 tablet of Denosyl Tablets for Large Dogs
Denosyl for Large Dogs	Body Weight (kg)
	16 to 29.9	1 tablet*
	30 to 54.9	2 tablets
	Over 55	3 tablets
	*Or 2 tablets of Denosyl Tablets for Medium Dogs

For optimal absorption, tablets should be given on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. For those owners who have difficulty administering tablets to their pets, Denosyl Tablet(s) may be disguised in a small bite of food. Studies have shown that, in many cases, tablets or capsules given as a "dry swallow" do not pass into the stomach in cats but may become lodged in the esophagus. It is therefore recommended that pet owners administer a few mLs of water immediately following any tablet administration to speed passage of the tablet into the stomach._If the pet is to receive more than one tablet daily, the total number of tablets may be divided between morning and evening for ease of administration._For example, a daily administration of three tablets could be divided into two tablets in the morning and one tablet in the evening.

Side Effects
Denosyl demonstrates a wide margin of safety.

Withholding Times
Nil

First Aid / Poisoning
If swallowed do NOT induce vomiting. For advice contact the National Poisons Centre 0800 POISON (0800 764766) or a doctor immediately. If skin or hair contact occurs remove contaminated clothing and flush skin and hair with running water.

Storage Conditions and Other Information
Store in a dry place below 25°C (air conditioning). Keep tablets in original blister pack until used. Tablets are sensitive to moisture and extreme heat and should not be split or crumbled.

Registration
Restricted Veterinary Medicine – Registered pursuant to the ACVM Act 1997 No. A9838, A9839, A9840.
See www.nzfsa.govt.nz/acvm for registration conditions.

Copyright Phoenix Pharm Distributors Ltd 2011 | Designed by Ad-Vent Marketing Ltd