Gentamax 100
Broad Spectrum Antibiotic.
Composition
Contains: Gentamicin 100 mg/mL (as the sulphate)
Features and Benefits
Gentamicin is an aminoglycoside antibiotic which is bactericidal by inhibiting protein synthesis in susceptible bacteria. Gentamicin is not significantly bound by animal protein and hence provides useful concentrations in peritoneal and pleural fluids. Its clearance rates may be reduced in cases of renal impairment, and prolonged courses are considered to be potentially nephrotoxic.
Gentamicin should only be used when the target bacterial species is known to be sensitive to this antibiotic.
Gentamicin is effective against a range of gram negative bacteria including:
actinobacillus spp, klebsiella spp, bordetella bronchiseptica, enterobacter spp, pseudomonas spp, e.coli.
Indications
Gentamicin is indicated in infections in horse, dogs, and cats which are known to be responsive to Gentamicin.
GENTAMICIN is rapidly absorbed following parenteral administration but reaches only low concentrations in the CSF and eye. Peak serum concentrations are reached within 30 -60 minutes after intramuscular injection. Therapeutic plasma concentrations are maintained in the horse for up to 6 hours following intramuscular injection. Gentamicin crosses the placenta. Excretion is primarily by by glomerular filtration.
Because of its rapid absorption after administration, and rapid bactericidal action, Gentamicin is particularly useful in acute infections, particularly of the urinary tract, reproductive tract and respiratory system.
Precautions
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Administration should not exceed 5 days.
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Do not use in animals with impaired renal function.
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Avoid using in very small cats and dogs as there is a risk of overdosing due to the very small injection volumes required.
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Use only in situations where sensitivity indicates that there is no suitable alternative antibiotic.
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Do not use in pregnant animals, as gentamicin crosses the placenta.
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Dosage and Administration
Cats and Dogs
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5mg/kg (0.5mL/10kg) twice on the first day then once daily
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Horses
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1.5 mg/kg every eight hours
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Mares
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Intra-uterine infusion 20-25mL (2 - 2.5g), diluted in 250 - 500mL sterilel saline. Infuse daily for 3 -5 days during oestrus.
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Withholding Period
Horses producing meat and offal for human consumption must not be sold for slaughter during or within 63 days of the last treatment.
Storage
Store below 25 degree C (air conditioning). Protect from light.
Presentation
100 mL sterile injectable solution, glass vial.
Registration
Prescription Animal Remedy (P.A.R) class 1, for use only under the authority or prescription of a veterinarian. Registered pursuant to the ACVM Act 1997 no. A9478.
See www.nzfsa.govt.nz/acvm for registration conditions.
Registered to:
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Nature Vet Pty Ltd
11 Moores Rd, Glenorie, NSW, Australia 2157
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NZ Agent & Distributor:
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Vetpharm (NZ) Ltd
PO Box 31363, Mairangi Bay, Auckland
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